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Clinical Trials/NCT06663150
NCT06663150
Not Yet Recruiting
N/A

Effectiveness of a Health Intervention With a Socio-community Approach on Frailty in Older Adults With Pre-frailty

Keralty SAS. Colombia0 sites160 target enrollmentNovember 15, 2024

Overview

Phase
N/A
Intervention
Not specified
Conditions
Frail Elderly Syndrome
Sponsor
Keralty SAS. Colombia
Enrollment
160
Primary Endpoint
Score on the FRAIL Scale
Status
Not Yet Recruiting
Last Updated
last year

Overview

Brief Summary

The objective of this study is: To evaluate the effectiveness of a health intervention with a socio-community approach on frailty in older adults with pre-frailty.

Specific Objectives:

To characterize the study population according to sociodemographic and clinical variables.

To evaluate the effect of the intervention on the functionality domain at 3 and 6 months.

To evaluate the effect of the intervention on the cognitive-emotional domain at 3 and 6 months.

To evaluate the effect of the intervention on the socio-community domain at 3 and 6 months.

To evaluate the effect of the intervention on frailty in older adults. To determine the proportion of participants hospitalized during the study period.

To determine the proportion of participants who visited the emergency room during the study period.

To determine the proportion of participants in long-term care facilities. To determine the proportion of adverse events associated with the intervention.

Study Hypothesis

The mean frailty score pre-intervention is equal to the mean frailty score post-intervention.

The mean frailty score pre-intervention is different from the mean frailty score post-intervention.

Registry
clinicaltrials.gov
Start Date
November 15, 2024
End Date
November 30, 2026
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Keralty SAS. Colombia
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Individuals ≥ 60 years old classified as pre-frail in the last 3 months and documented in their medical history.
  • Individuals who meet the requirements and provide voluntary informed consent for their participation.
  • Individuals available to remain in Bogotá D.C. during the study period.

Exclusion Criteria

  • Individuals receiving care at community-focused medical centers.
  • Individuals attending community dining programs, physical activity programs, community groups, care blocks, volunteering, or other related activities.
  • Individuals who have experienced falls in the last 6 months with clinical consequences (hospitalization, fractures, traumatic brain injury).
  • Individuals with a clinical history of moderate cognitive impairment, neurodegenerative diseases (e.g., Parkinson's disease), and/or neuro-musculoskeletal disorders, active cancer, end-stage renal disease, unstable ischemic heart disease, uncontrolled arrhythmias, severe aortic stenosis, uncontrolled hypertension (\>180/100 mmHg), or advanced heart failure, exacerbation of chronic diseases (COPD, heart failure), unrehabilitated severe hearing loss, deafness, or blindness with communication limitations.
  • Acute conditions requiring hospitalization, such as acute myocardial infarction or urinary tract infections.
  • Bone fractures in the last 3 months.
  • Individuals unable to follow instructions or with behavioral changes that hinder their participation in the study.
  • Individuals with severe psychiatric illness that, in the physician's judgment, prevents proper adherence to the study intervention.
  • Institutionalized individuals in long-term care facilities.

Outcomes

Primary Outcomes

Score on the FRAIL Scale

Time Frame: Baseline, 3, 6 Months

Frailty will be assessed using the FRAIL Scale, which evaluates five domains: fatigue, resistance, ambulation, illnesses, and weight loss. The total score ranges from 0 to 9, where higher scores indicate greater frailty

Secondary Outcomes

  • Barthel Index(Baseline, 3, 6 Months)
  • Lawton Score(Baseline, 3, 6 Months)
  • Downton Scale(Baseline, 3, 6 Months)
  • Score on the Montreal Cognitive Assessment (MoCA)(Baseline, 3, 6 Months)
  • Score on the Yesavage Geriatric Depression Scale (GDS)(Baseline, 3, 6 Months)
  • Score on the Gijón Family-Social Assessment Scale(Baseline, 3, 6 Months)
  • Score on the Lubben Social Network Scale(Baseline, 3, 6 Months)
  • Health-Related Quality of Life Measured by EQ-5D-3L(Baseline, 3, 6 Months)
  • Number of Hospital Admissions(During the 6-month intervention)
  • Total Number of Hospitalization Days(During the 6-month intervention)
  • Total Number of Emergency Room Admissions(During the 6-month intervention.)
  • Requirement for Admission to Long-Term Care Facilities(During the 6-month intervention.)
  • Utilization of Social Health Assets(During the 6-month intervention.)

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