The potency of Edoxaban, a blood thinner, in patients with liverdisease.
- Conditions
- cirrhosis, anticoagulation
- Registration Number
- NL-OMON26370
- Lead Sponsor
- niversity Medical Center groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 32
Inclusion Criteria
•Age > 18 yrs
•Child Pugh A or B cirrhosis
Exclusion Criteria
•Malignancies
•Renal failure requiring intervention with drugs or dialysis
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method the percentual difference in thrombin generation capacity of plasma taken at baseline versus plasma taken at steady state
- Secondary Outcome Measures
Name Time Method the number of adverse events and the plasma levels of Edoxaban compared to an anti-Xa assay (calibrated for Edoxaban).