临床试验/NCT01418833

NCT01418833已完成不适用

Preliminary Experience of Routine Voriconazole Therapeutic Drug Monitoring (TDM) in a Tertiary Care Centre.

Universitaire Ziekenhuizen KU Leuven1 个研究点分布在 1 个国家目标入组 160 人开始时间: 2010年10月最近更新: 2015年2月9日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: Universitaire Ziekenhuizen KU Leuven
入组人数: 160
试验地点: 1
主要终点: Voriconazole plasma levels during routine intravenous and oral therapy

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The first goal of this study is to map all the subtherapeutic, therapeutic and supratherapeutic voriconazole plasma levels in the University Hospitals Leuven. The second objective is to optimize and validate guidelines for dose modifications in patients with too low or high plasma concentrations and to investigate if the same guidelines can be used in different patient populations.

研究设计

研究类型: Observational
观察模型: Case Only
时间视角: Prospective

入排标准

性别: All
接受健康志愿者: 否

入选标准

•Patients treated with voriconazole
•at least 1 voriconazole plasma level measured during therapy

排除标准

未提供

结局指标

主要结局

Voriconazole plasma levels during routine intravenous and oral therapy

时间窗: trough levels every 4 days after start or dose adjustment of voriconazole

次要结局

未报告次要终点

研究者

发起方

Universitaire Ziekenhuizen KU Leuven

申办方类型

Other

责任方

Principal Investigator

主要研究者

Ap.r Kim Vanstraelen

Hospital Pharmacist

Universitaire Ziekenhuizen KU Leuven

研究点 (1)

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