Physical ExeRcise Following Esophageal Cancer Treatment (PERFECT) Study: a randomized clinical trial

Completed

• Conditions: cancer of the esophagus; esophageal cancer; 10017991; 10017998

• Registration Number: NL-OMON47661
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2019-12-06
• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 120

Inclusion Criteria

- Patients after EC resection with curative intent, with or without neoadjuvant
chemoradiation
- Patients *18 years of age
- Patients with sufficient Dutch writing and reading skills
- Patients who exercise * 150 min/week
- Karnofsky Performance status *60
- Able to walk *60 m

Exclusion Criteria

- Presence of metastatic disease
- Contraindication for physical activity on the Revised Physical Activity
Readiness Questionnaire (PARQ)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Health-related quality of life. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Functional wellbeing and symptoms<br /><br>- Esophagus-specific QoL<br /><br>- Fatigue<br /><br>- Anxiety and depression<br /><br>- Diet<br /><br>- Sleep quality<br /><br>- Physical activity<br /><br>- Body composition<br /><br>- Work ability<br /><br>- Blood markers (e.g. inflammatory markers)<br /><br>- Physical fitness (cardiorespiratory fitness, muscle strength)<br /><br>- Cancer recurrence<br /><br>- Overall survival</p><br>