ew Therapeutic Strategies in Patients with SARS-COV-2-Induced Severe Pneumonia. - SARITA 2: SARITA (Síndrome Aguda Respiratória)

Ministério da Ciência, Tecnologia, Inovações e Comunicações (MCTIC)0 个研究点开始时间: 2020年8月24日最近更新: 2023年5月29日

适应症

试验速览

暂无简介。

•Patients who meet the requirements for the diagnosis of Coronavirus infection [Characteristic respiratory symptoms (dry cough, fever) associated with a tomographic image of pneumonia compatible with COVID-19 without acute respiratory failure (Oxygen Saturation less than 93% with nasal oxygen catheter at 5 liters / minute); Patients who meet the requirements for the diagnosis of Coronavirus infection [Characteristic respiratory symptoms (dry cough, fever) associated with a confirmatory molecular test for COVID-19 without acute respiratory failure (Oxygen Saturation less than 93% with a 5 liter nasal oxygen catheter /minute); Age greater than or equal to 18 years old man or woman; In women with negative pregnancy test and commitment to the use of contraception throughout the study (provided by the researcher); Willing to take study medication; Able to provide written, informed and / or informed consent even to a family member.

•It is not possible to take drugs orally or through a gastroenteric feeding tube; With significantly abnormal liver function (Child Pugh C); Previous renal failure: patients who previously underwent dialysis, or patients with GFR less than or equal to 30 mL / min / 1.73 m2; NYHA (New York Heart Association) heart failure 3 or 4; COPD GOLD 3 and 4; Neoplasia; Autoimmune disease; Individuals with known hypersensitivity to study drugs; People who have already been treated with the study drug during the last 30 days; Clinical or radiological suspicion of tuberculosis and bacterial pneumonia.

发起方

Ministério da Ciência, Tecnologia, Inovações e Comunicações (MCTIC)