Effect of coenzyme Q10 supplement on chronic gingivitis inflammation in diabetic patients
Not Applicable
- Conditions
- Controlled diabetes.E10.6Type 1 diabetes mellitus with other specified complications
- Registration Number
- IRCT20180630040290N4
- Lead Sponsor
- Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 42
Inclusion Criteria
Diabetic patients referred to the periodontitis Department of Tabriz Dental School
Having informed consent
Having age 29 to 59
Exclusion Criteria
People with systemic disease
Pregnant women
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pocket Depth. Timepoint: Before the intervention , one months after initiating the intervention. Method of measurement: A periodontal probe is used to measure this parameter. The first sign visible at the top of the envelope is the depth of the envelope.;Clinical Attachment Level. Timepoint: Before the intervention , one months after initiating the intervention. Method of measurement: The clinical adhesion of the gums is obtained by the difference between the distance from the gingival margin to the plaque floor from the CEJ distance to the gingival margin.
- Secondary Outcome Measures
Name Time Method Plaque index. Timepoint: Before the intervention , one months after initiating the intervention. Method of measurement: Plaque index is obtained from dividing the number of levels with plaque on the total number of multiplication levels in 100 .;Bleeding index. Timepoint: Before the intervention , one months after initiating the intervention. Method of measurement: Bleeding index (BI) is measured using the University of North Carolina probe_15 (UNC-15) probe.
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie CoQ10's anti-inflammatory effects in diabetic chronic gingivitis (IRCT20180630040290N4)?
How does CoQ10 supplementation with SRP compare to SRP alone in reducing gingival indexes in controlled diabetes (E10.6)?
Which biomarkers correlate with improved periodontal outcomes in IRCT20180630040290N4 diabetic patients receiving CoQ10?
What adverse events are associated with CoQ10 in periodontal therapy for controlled diabetes, and how are they managed?
Are there synergistic effects of CoQ10 with other antioxidants like vitamin C or omega-3 fatty acids in treating diabetic gingivitis?