Evaluation of Bladder Volumes in Patients Receiving Radiotherapy to the Rectum, Using Kilovoltage Cone-beam Imaging
- Conditions
- Rectal Cancer
- Registration Number
- NCT01033682
- Lead Sponsor
- Royal Marsden NHS Foundation Trust
- Brief Summary
The purpose of this study is to implement and access a newly developed bladder filling protocol for patients receiving radiotherapy for rectal cancer using imaging on the treatment unit.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
- Patients receiving radical radiotherapy to rectal malignancies.
- Age > 18 years old
- No previous lower GI radiotherapy
- Written informed consent according to good clinical practice (GCP) and national / local regulations.
Exclusion Criteria
- Patients receiving palliative radiotherapy to rectal malignancies.
- Patients receiving radical short course preoperative radiotherapy for rectal malignancies.
- Patients unable to give informed consent.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The percentage of patients who are able to achieve a bladder volume within +/- 30% of planning volume, on all treatment CBCT (cone beam computed tomography) scans
- Secondary Outcome Measures
Name Time Method The per-patient standard deviation of bladder volume throughout the course of radiotherapy The percentage of patients who are unable to follow the bladder filling protocol at any point during their treatment. The correlation between bladder volume and small bowel volume planning target volume
Trial Locations
- Locations (1)
Royal Marsden NHS Foundation Trust
🇬🇧Sutton, Surrey, United Kingdom