Treatment of the skin manifestations of Darier's disease by the topical application of COX-2 inhibitors
Not Applicable
- Conditions
- Darier's disease
- Registration Number
- JPRN-UMIN000015905
- Lead Sponsor
- Department of Dermatology, Keio University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
Not provided
Exclusion Criteria
1) Patients without disease notification 2) Patients who do not join "Development of the genetic diagnosis system of congenital and Inherited skin disorders (UMIN000009851)" 3) Aspirin-induced asthma patients 4) Patients with diclofenac sodium allergy 5) Pregnant women
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement of skin manifestations which are evaluated by Psoriasis Area and Severity Index score after 3-month treatment
- Secondary Outcome Measures
Name Time Method Safety evaluation: Common terminology criteria for adverse events v4.0 grade 3-5 Therapy evaluation: Pathological findings and level of expression of ATP2A2 after 3-month treatment