The Asymmetry of Endometriotic Lesions as Demonstration of the Theory of Menstrual Reflux and Anatomical Niches: Italian Multicenter Study by the ETIC Group
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 2,000
- 试验地点
- 1
- 主要终点
- Asymmetric distribution of endometriotic lesions on paired pelvic organs
研究概览
简要总结
This study aims to understand whether endometriosis lesions - and tumors that can arise in association with endometriosis - occur more often on one side of the pelvis than the other.
During surgery, doctors will record the exact location of each lesion to see if there is a consistent right- or left-sided pattern.
Understanding these patterns may help improve knowledge about how endometriosis develops (pathogenesis), and thus improve its treatment.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •age ≥18 years at the time of histological diagnosis of endometriosis
- •patients undergoing surgery with endometriotic lesions or patients with endometriotic lesions associated with endometrioid or clear cell ovarian cancer (Stage I-II) or borderline seromucinous ovarian cancer
- •first operation for endometriosis in the reference center (if recurrence consider only if both operations were performed at the reference center).
排除标准
- •age <18 years
- •patients affected by Stage I-II endometrioid or clear cell carcinoma or seromucinous borderline ovarian cancer not associated with endometriosis or in a more advanced stage of disease
- •women with an ultrasound diagnosis of endometriosis who have not undergone surgery
- •previous operations for endometriosis performed at another center
结局指标
主要结局
Asymmetric distribution of endometriotic lesions on paired pelvic organs
时间窗: At the time of index surgery
Proportion of patients presenting an asymmetric (right- or left-sided) distribution of endometriotic lesions on even and symmetrical pelvic organs (e.g., ovaries, uterosacral ligaments), based on the laterality observed and described during the index surgical procedure. Side-specific frequencies (right vs left) will be reported as number and percentage.
次要结局
- Asymmetric distribution of malignant ovarian lesions related to endometriosis(At the time of index surgery)