The efficacy and safety of Delphini Acne Control in the treatment of mild severity of acne vulgaris: a non-inferiority randomized-controlled trial

Phase 3

Completed

• Conditions: Patients with mild acne; Acne

• Registration Number: TCTR20230809001
• Lead Sponsor: Department of Biochemistry Faculty of Science, Chulalongkorn University

Brief Summary

Delphini Acne control was non inferior to 0.025% tretinoin in reduction of acne. Delphini Acne control cream induced less skin dryness and acne flare compared to tretinoin.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-08-09
• Study Completion: 2023-09-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

Healthy patients with mild acne

Exclusion Criteria

On oral or topical acne medication
On oral contraceptive pills
On oral medication that have systemic hormonal effect e.g. finasteride, dutasteride, spironolactone

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Acne lesion count baseline, 4 weeks, 8 weeks, 12 weeks Count

Secondary Outcome Measures

Name	Time	Method
Skin Hydration baseline, 4 weeks, 8 weeks, 12 weeks Corneometer,Transepidermal Water Loss (TEWL) baseline, 4 weeks, 8 weeks, 12 weeks Tewameter,Skin Sebum level baseline, 4 weeks, 8 weeks, 12 weeks Sebumeter