The assessment of the therapeutic effect of bee propolis on oral Lichen Planus treatment.

Phase 3

Recruiting

• Conditions: ichen planus.

• Registration Number: IRCT20210112050013N2
• Lead Sponsor: Bojnourd University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 12 July 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Patients who are diagnosed with OLP by an oral specialist.
People who have been willing to participate in the study and sign the informed consent form.

Exclusion Criteria

Patients with any past or present immunological disease or disorder.
Patients with any past or present allergic disease or disorder.
Pregnant and lactating women.
Susceptible Patients to bee sting and products.
Patients who have used systemic or topical Glucocorticosteroids at least over the past one month.
Patients with Lichen Planus extra-oral manifestations.
Patients with any continuous medication history.
Patients with oral Lichen Planus with evidence of dysplastic changes in the oral mucosa or a history of such changes in the past.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Extent of Atrophic areas: The area of Atrophic areas measured by caliper in square millimeters.Extent of Ulcerative areas: The area of the wound area measured by the caliper. Area of Keratotic areas: Area of Keratotic areas measured by caliper. Intensity of pain and irritation: The scale of pain and oral mucosa irritation that the patient reports according to VAS. Timepoint: At the beginning of study and a month after the start of the study. Method of measurement: To measure the area of the affected areas, the largest lesion diameters are measured by a caliper and their product is considered as the area of the target area. If the patient has similar lesions in several areas, the area of all these areas will be added together and this amount will be reported. The scale of pain and irritation is measured by the Visual Analogue Scale. This method of measurement asks the patient to rate their pain and irritation from 0 (with no pain and irritation) to 10 (the most severe pain and irritation).