Effects of Spinal Manipulation on Vertebrobasilar and Internal Carotis Arteries in Healthy Population

Not Applicable

Completed

• Conditions: Vertebral Artery Dissection, Traumatic; Neck Pain

• Registration Number: NCT03435159
• Lead Sponsor: Bahçeşehir University

Brief Summary

After lumbar pain, neck pain is the most common cause of patients needing chiropractic care; the second most common cause of spinal manipulation use (1). Manipulation and mobilization are commonly used by chiropractors, osteopaths and manipulative physiotherapists in the treatment of neck pain. Many studies show that the Activator instrument is also used for this purpose in the chiropractic profession (2) There are several published case reports that relate to neck manipulation to vertebral artery dissection and stroke. The prevailing theory is that the neck extension and / or rotation may damage the vertebral artery in the foramen transversarium, especially at the C1-C2 level (2). However, most cases of extracranial vertebral artery dissection are thought to be spontaneous (3).

In the literature, there have been no studies investigating the effects of instrument-assisted spinal manipulation on vertebrobasilar and internal carotis arteries. the aim of this study to compare the effect of manual and instrumental spinal manipulation on blood flow parameters of vertebrobasilar and internal carotis arteries on healthy persons which have mechanical neck pain and asymptomatic in vertebrobasilar insufficiency test.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-02-17
• Primary Completion: 2017-04-28
• Study Completion: 2017-04-28
• Study First Submitted: 2018-01-03
• Status Verified: 2018-02
• Study First Submitted QC: 2018-02-14
• Last Update Submitted: 2018-02-14
• Study First Posted: 2018-02-15
• Last Update Posted: 2018-02-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Being between 20-40 years of age
• Having non-specific mechanical neck pain for more than 3 months with symptoms provoked by neck postures, movements, or palpation
• Willingly participating to the study
• Signing the confirmation form.

Exclusion Criteria

• Spinal root compression (radiculopathy)
• Neurological symptoms like weakness and numbness in extremities and face, uncontrolled movements, abnormal gait, dizziness, undefined nausea/vomiting, swallowing and speaking difficulties
• Acute inflammatory disease
• Spontaneously vertebral artery dissection in family
• Tested positive in premanipulative vertebrobasilar artery insufficiency test
• Being on anticoagulant and antiaggregant medication.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Change in Peak Systolic Velocity (PSV)	1 minute	cm/s, measured in each group
Change in End Diastolic Velocity (EDV)	1 minute	cm/s, measured in each group
Change in Resistive Index (RI)	1 minute	The Formula: RI = (PSV- EDV) / PSV, it has no unit, measured in each group
Change in Volume Flow (VF)	1 minute	ml/min, measured only for right and left vertebral arteries

Trial Locations

Locations (1)

Maslak Acıbadem Hospital; 🇹🇷 Istanbul, Turkey