se of MRI in diagnosing the cause of Myocardial Infarction (Heart Attack) in patients with no coronary artery obstructio
Not Applicable
- Conditions
- Health Condition 1: I21A- Other type of myocardial infarction
- Registration Number
- CTRI/2021/06/034203
- Lead Sponsor
- Rajiv Gandhi University of Health Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1) Consecutive adult patients (age 18 years and above) clinically diagnosed as Myocardial Infarction who have undergone CAG or CT CAG and found to have non obstructed coronaries
2) Those who will undergo CMR within 1 week of symptom onset
Exclusion Criteria
1) Patients admitted with suspected heart failure
2) Arrhythmic events at presentation
3) False troponin elevation
4) History of chronic troponin elevation
5) Any patient with standard contraindication to MRI/ poor MRI quality
5) Any patient with prior cardiac history for example myocarditis myocardial infarction or other known cardiomyopathies.
6) Pediatric patients (age < 18 years)
7) Patients with MRI after one week of symptom onset.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To estimate the proportion of MINOCA patients in whom an etiological diagnosis can be established by MRI. <br/ ><br>Timepoint: 6 months: <br/ ><br>Recruitment of 50 % of patients of the study <br/ ><br> <br/ ><br>12 months: <br/ ><br>Completion of patient recruitment <br/ ><br>Follow up of already recruited patients <br/ ><br> <br/ ><br>18 months: <br/ ><br>Complete follow up of all patients for mortality <br/ ><br> <br/ ><br>24 months: <br/ ><br>Completion of data analysis
- Secondary Outcome Measures
Name Time Method 1) To estimate the proportion of patients with ischemic etiology for MINOCA. <br/ ><br>2) To estimate the proportion of various non ischemic causes for MINOCA <br/ ><br>3) To assess 6 months to 1 year MACE in these patients. <br/ ><br>Timepoint: 6 months: <br/ ><br>Recruitment of 50 % of patients of the study <br/ ><br> <br/ ><br>12 months: <br/ ><br>Completion of patient recruitment <br/ ><br>Follow up of already recruited patients <br/ ><br> <br/ ><br>18 months: <br/ ><br>Complete follow up of all patients for mortality <br/ ><br> <br/ ><br>24 months: <br/ ><br>Completion of data analysis