Effect of Protein Blend Supplementation During Exercise Training on Muscle Growth and Strength

Not Applicable

Completed

• Conditions: Muscle
• Interventions: Dietary Supplement: Blend; Dietary Supplement: Placebo; Dietary Supplement: Whey

• Registration Number: NCT01749189
• Lead Sponsor: DuPont Nutrition and Health

Brief Summary

This study will investigate the effects of a soy/dairy protein blend on muscle growth and strength. In sports nutrition and in aging it is important to have healthy muscles. This can be achieved with exercise and nutrition. Consumption of protein following resistance exercise can promote healthy muscle growth and help improve strength. Young healthy men will be studied during a 12 week resistance exercise training program and be given protein supplements every day during the study. The hypothesis is that a blend of soy, whey and casein will induce a greater muscle gain and strength increase than the control.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-07
• Study First Submitted: 2012-11-15
• Study First Submitted QC: 2012-12-12
• Study First Posted: 2012-12-13
• Primary Completion: 2014-05
• Study Completion: 2014-06
• Status Verified: 2019-10
• Last Update Submitted: 2019-10-03
• Last Update Posted: 2019-10-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 58

Inclusion Criteria

• Stable body weight, healthy, males aged 18-35

Exclusion Criteria

1. Exercise training (>2 weekly sessions of moderate to high intensity aerobic or resistance exercise)
2. Resistance Training (>2 weekly sessions of moderate to high intensity) within the past six months
3. Any orthopedic injury that prohibits participation in the exercise training
4. Significant heart, liver, kidney, blood, or respiratory disease
5. Peripheral vascular disease
6. Diabetes mellitus or other untreated endocrine disease
7. Active cancer (all groups) and history of cancer
8. Acute infectious disease or history of chronic infections (e.g. TB, hepatitis, HIV, herpes)
9. Recent (within 6 months) treatment with anabolic steroids, or corticosteroids.
10. Alcohol or drug abuse
11. Tobacco use (smoking or chewing)
12. BMI range will be (20-29.9 kg/m2) to exclude for Malnutrition (hypoalbuminemia, and/or hypotransferrinemia) and Obesity
13. Low hemoglobin levels (below normal values)
14. Food allergies (including milk and soy)
15. Individuals on a Vegetarian Diet
16. Females
17. Average protein intake < 0.6 or >1.8 g/kg per day
18. Taking dietary supplements such as green tea, creatine, ribose, whey or soy protein, etc. within the past 6 months
19. Currently on a high-soy diet or high dairy diet (consuming >2 servings of soy per day or >6 servings of dairy)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Blend	Blend	A dry blended beverage containing a protein blend of soy, whey and casein
Placebo	Placebo	Placebo dry blended beverage (carbohydrate)
Whey	Whey	A dry blended beverage containing Whey protein

Primary Outcome Measures

Name	Time	Method
Change in Muscle Mass	Baseline, 6 weeks, 12 weeks	Muscle Mass will be determined by DEXA

Secondary Outcome Measures

Name	Time	Method
Change in Muscle Strength	Baseline, 6 weeks, 12 weeks	Knee Extensor

Trial Locations

Locations (1)

University of Texas Medical Branch; 🇺🇸 Galveston, Texas, United States