Identification of Corticomedullary Differentiation Along Different Stage of Pregnancy
试验速览
- 阶段
- 不适用
- 入组人数
- 330
- 试验地点
- 1
- 主要终点
- CMD presence
研究概览
简要总结
Corticomedullary differentiation (CMD) abnormality (absent/reversed) is a parameter that can indicate possible nephropathy. The evolution of CMD across gestation had not been well established. Devrendt et al demonstrated the presence of CMD in all fetuses older then 20 weeks. In our study we would like to determine the exact timing of it's sonographic visualisation. This is a prospective study recruiting women between 14-24 week gestation during routine ultrasound screening. A midsagittal image of each kidney will be taken by a single sonographer and examined for the presence of the CMD by two other sonographers blinded to gestational age.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •pregnant women 14-24 weeks
- •singleton pregnancy
- •Appropriate for gestational age fetuses
- •well dated pregnancy
排除标准
- •family history of renal disease
- •small /large for gestational age fetuses
- •known structural anomalies
- •unknown dating
结局指标
主要结局
CMD presence
时间窗: A single exam for each participent. The photos will be reviewed within up to 6 month from examination date
次要结局
未报告次要终点