Amniotic Membrane Transplantation vs Conjunctival–Limbal Autograft for Primary Pterygium
Phase 2
Completed
- Conditions
- Primary Pterygium
- Registration Number
- RPCEC00000081
- Lead Sponsor
- Hermanos Ameijeiras General Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 221
Inclusion Criteria
Patients with primary pterigium grade II or higher. Cubans. Over 15 years of age.
Exclusion Criteria
With recurrent pterigium of any grade Previous corneal perforation or perforating trauma. Suspected conjunctival malignancy. Corneal leucoma. Any corneal inflammatory or degenerative disease. Background of allergy to topic steroids or Sjögren syndrome. If a patient presents pterigium in both eyes, only the worst eye will be included.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie the efficacy of amniotic membrane transplantation in primary pterygium treatment?
How does conjunctival-limbal autograft compare to amniotic membrane transplantation in pterygium recurrence rates and visual outcomes?
Are there specific ocular surface biomarkers that predict response to amniotic membrane or limbal graft interventions for pterygium?
What are the long-term safety profiles and management strategies for complications after amniotic membrane vs limbal autograft procedures?
What combination therapies or alternative approaches are being explored alongside amniotic membrane for primary pterygium management?