NCT01805232Unknown4 期
Intravenous Artesunate Versus Quinine in Severe Malaria at Kassla, Sudan
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- clearance of the parasite and fever
研究概览
简要总结
Intravenous artesunate is egual to quinine in the treatment of severe malaria
详细描述
Intravenous artesunate is egual to quinine in the treatment of severe malaria in the form of fever clearance time and parasite clearance time
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 1 Year 至 80 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •severe P.falciparum malaria-
排除标准
- •mixed infection Pregnant women -
研究组 & 干预措施
artesunate
Experimental
intravenous artesunate 80 mg/kg initially then after 8 hours then daily
干预措施: artesunate (Drug)
artesunate
Experimental
intravenous artesunate 80 mg/kg initially then after 8 hours then daily
干预措施: Quinine (Drug)
quinine
Active Comparator
quinine infusion 80 mg/kg every 8 hours
干预措施: artesunate (Drug)
quinine
Active Comparator
quinine infusion 80 mg/kg every 8 hours
干预措施: Quinine (Drug)
结局指标
主要结局
clearance of the parasite and fever
时间窗: 3 days
To compare the parasite clearance time and fever clearance time between the two groups
次要结局
未报告次要终点
研究者
Ishag Adam
Professor
University of Khartoum
研究点 (1)
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