Epidemiology of Sudden Cardiac Arrest in Sub-Saharan Africa: Rationale and Design

• Conditions: Cardiovascular Diseases

• Registration Number: NCT02142270
• Lead Sponsor: Cameroon Resuscitation Council

Brief Summary

Background The burden of sudden cardiac death (SCD) in Africa is unknown. Our aim is to assess the epidemiology of SCD in Africa. Methods The sub-Saharan Africa SCD study is a prospective, multicenter, community-based registry monitoring all cases of cardiac arrest occurring in victims \> 15 years old. Investigators will use the definition of established SCD if an unexpected death without obvious extracardiac cause, occurred with a rapid witnessed collapse, or if unwitnessed, occurred within 1 hour after the onset of symptoms; probable SCD if an unexpected death without obvious extracardiac cause occurred within the previous 24 hours. After approval from institutional boards, Investigators will record demographic, clinical, electrocardiographic and biological variables of SCD victims (including survivors of cardiac arrest) in several sub-Saharan African cities. All deaths occurring in residents of districts of interest will be checked for past medical history, circumstances of death, and autopsy report (if possible). Investigators will also analyze the employment of resuscitation attempts during the timeframe of sudden cardiac arrest (SCA) in various patient populations throughout countries. Conclusion This study will provide comprehensive, contemporary data on the epidemiology of SCD in sub-Saharan Africa and will help in the development of strategies to prevent and manage cardiac arrest in this region of the world.

Detailed Description

Not available

Study Timeline

• Status Verified: 2014-05
• Study First Submitted: 2014-05-10
• Study First Submitted QC: 2014-05-19
• Last Update Submitted: 2014-05-19
• Study First Posted: 2014-05-20
• Last Update Posted: 2014-05-20
• Study Start: 2015-01
• Primary Completion: 2016-01
• Study Completion: 2018-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 250000

Inclusion Criteria

• Victims of cardiac arrest, either SCD or aborted SCA

Exclusion Criteria

• Age ≤ 15 years.
• Refusal of consent (by the family).

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sudden Cardiac Death	3 years

Trial Locations

Locations (1)

Bonny; 🇨🇲 Douala, Cameroon