跳至主要内容
临床试验/NCT03673033
NCT03673033已完成不适用

Can the Effects of Cold and Hot Ischemia Time on Biliary Complications in Live Donor Liver Transplantation Be Classified?

Inonu University1 个研究点 分布在 1 个国家目标入组 99 人开始时间: 2018年3月10日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
99
试验地点
1
主要终点
development of biliary complication in the first month after liver transplantation

研究概览

简要总结

The study was designed as a prospective cohort study. The effects of hot and cold ischemic times during live donor liver transplantation on postoperative 1-3 and 6 month follow up biliary complications will be investigated.

详细描述

The invastigators will record the age, gender, weight, diagnosis, presence of hcc (hepatocellular carcinoma), whether transcatheter embolization (transarterial radiolabelization) is performed, meld score, age of donor, gender, graft hepatic artery diameter, bile duct diameter and number before surgery.

During the operation,

The duration of ischemia will be evaluated as three stages.

During the first stage donor hepatectomy, the time from the interruption of the hepatic artery to the first administration of the solution to the bile ducts on the back table will be recorded and recorded as the first ischemia time.

The time from the administration of the solution to the biliary system on the stage 2 back-to-back table until the cold anastomosis is performed will be recorded as the duration of cold ischemia.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Live donor liver transplantation Emergency Live donor liver transplantation Multiple or single bile duct anastomosis in liver transplantation

排除标准

  • Hepaticojejunostomy Cadaveric liver transplantation Pediatric liver transplantation Cmv infection presence Hepatic arterial thrombus Porta thrombus Acute rejection

结局指标

主要结局

development of biliary complication in the first month after liver transplantation

时间窗: 1 month

biliary complication at the first month after transplantation and whether this complication is interfered with or not will be evaluated.

次要结局

  • development of biliary complication in the six month after liver transplantation(6 months)
  • development of biliary complication in the three months after liver transplantation(3 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

cihan gokler

Principal invastigator

Inonu University

研究点 (1)

Loading locations...

相似试验