Comparison of Erector Spinae Plane and Paravertebral Nerve Blocks for Postoperative Analgesia in Children After the Nuss Procedure

West China Hospital1 site in 1 country68 target enrollmentSeptember 25, 2021

ConditionsNerve Block Analgesia Pectus Excavatum

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Nerve Block
Sponsor: West China Hospital
Enrollment: 68
Locations: 1
Primary Endpoint: Pain scores at rest at 24 hours postoperatively
Status: Completed
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This is a prospective randomized double-blind non-inferiority trial designed to test the hypothesis that erector spinae plane block (ESPB) is non-inferior to thoracic paravertebral block (TPVB) in postoperative pain control after pectus excavatum repair.

Registry

clinicaltrials.gov

Start Date

September 25, 2021

End Date

March 23, 2023

Last Updated

2 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

West China Hospital

Responsible Party

Principal Investigator

Min Xu

Department of Anesthesiology, West China Hospital, Sichuan University

West China Hospital

Eligibility Criteria

Inclusion Criteria

•Age between 4 to 18 years Scheduled for elective Nuss surgery Written informed consent is obtained from parents of each patient.

Exclusion Criteria

•Coagulation dysfunction. American Society of Anesthesiologists Physical Status 4 or
•Allergy to study medication. Local infection at the site of injection or systemic infection. Inability to understand Chinese.

Outcomes

Primary Outcomes

Pain scores at rest at 24 hours postoperatively

Time Frame: 24 hours postoperatively

Pain scores will be recorded using the Numeric Rating Scale (NRS) scores (0-10).

Secondary Outcomes

The pain degree at rest and after movement or coughing(dynamic)(at 3, 6, 12, 24, and 48 hours after surgery)
total rescue morphine-equivalent consumption per weight(at 24 and 48 hours after surgery)
Emergence agitation at 5, 15, 30 min after extubation(at 5, 15, 30 min after extubation)
Total dosage of intraoperative sufentanil and remifentanil(during surgery)
The time to first analgesia request(within the 3 days after surgery)
The time to first mobilization(within the 3 days after surgery)
Side effects(within the 5 days after surgery)