Relationship Between Serum Resistin Levels and Reduction in Visceral Fat in Patients Undergoing Sleeve Gastrectomy Due to Morbid Obesity
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Change in body mass index at 8 months
研究概览
简要总结
This study aims to investigate whether a specific protein in the blood, called resistin, can help doctors predict how much dangerous internal fat a patient will lose following weight loss surgery. Sleeve gastrectomy is a common and effective procedure that reduces the stomach's size to help patients lose weight and improve their metabolic health. Beyond just losing weight, it is vital to reduce visceral fat-the fat stored around internal organs-which is closely linked to inflammation and conditions like Type 2 Diabetes. Resistin is a marker known to contribute to insulin resistance and is typically higher in individuals with significant abdominal fat. By measuring resistin levels before surgery, we want to determine if this protein can serve as a guide to predict a patient's internal fat loss and overall metabolic recovery. Ultimately, this research could help healthcare providers better understand the hormonal changes that occur during weight loss and identify which patients may experience the most significant health improvements after the procedure.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 18 to 75
- •International Classification of Diseases (ICD) code E66 diagnosis (obesity)
- •Patients who have given consent for sleeve gastrectomy
- •Patients who are suitable for general anesthesia
排除标准
- •Patients who did not give consent to be included in the study
- •Patients who are scheduled for surgery other than sleeve gastrectomy
研究组 & 干预措施
Sleeve Gastrectomy Patients
Patients who meet inclusion criteria for the study undergoing sleeve gastrectomy
干预措施: Laparoscopic Sleeve Gastrectomy (Procedure)
结局指标
主要结局
Change in body mass index at 8 months
时间窗: 8 months after surgery
次要结局
- Change in visseral fat at 8 months(8 months after surgery)
- Change in basal metabolic rate at 8 months(8 months after surgery)
研究者
Sercan YUKSEL, MD
Associate Professor
Başakşehir Çam & Sakura City Hospital
