Diagnostic value of methylated SEPT9 and RNF180 for gastric cancer
- Conditions
- Collect plasma samples from patients diagnosed with benign gastric diseases and gastric cancer through endoscopic examination and histopathological examination, and evaluate the diagnostic value of mSEPT9 and mRNF180 alone or in combination for gastric cancer.diagnostic value, gastric cancer, methylation, SEPT9, RNF180
- Registration Number
- TCTR20240606001
- Lead Sponsor
- The First Affiliated Hospital of Kunming Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 201
1) All patients underwent endoscopic examination and histopathological examination, with complete clinical information; 2) Not receiving radiotherapy, chemotherapy, or gastric cancer related surgery; 3) no pregnancy.
1) Patients who have not undergone endoscopic examination and histopathological examination have incomplete clinical information; 2) Hemolytic samples; 3) Including incomplete history of gastric cancer surgery, other cancer history, or any history of chemotherapy or radiation therapy; 4) Pregnancy.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Combined diagnostic accuracy of methylated SEPT9 and RNF180 At the time that patients test with PCR Sensitivity, Specificity, PPV, NPV, AUROC
- Secondary Outcome Measures
Name Time Method Independent diagnostic accuracy of methylated SEPT9 or RNF180 At the time that patients test with PCR Sensitivity, Specificity, PPV, NPV, AURO
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