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A retrospective comparison of two types of dialysis machine for dialysis patients

Phase 3
Completed
Conditions
End stage renal disease (Hemodialysis patients)
Urological and Genital Diseases
Renal disease
Registration Number
ISRCTN12403265
Lead Sponsor
Renal Therapy Services
Brief Summary

2022 Results article in https://doi.org/10.1016/j.xkme.2022.100431 medium cutoff (MCO) versus high-flux (HF) dialysis membranes results (added 23/02/2022)

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
1098
Inclusion Criteria

1. End stage renal disease
2. Prevalent HD patient defined as having received HD for 90 days or more at the time of the cohort’s inception (01 September 2017 through 30 November 2017)
3. Enrolled in the COREXH registry between 01 September 2017 and 30 November 2017, or were treated via conventional high-flux HD during the same time period at the same renal centers, and with the same model of dialysis care
4. Undergoing HD at least 3 times per week and a minimum duration of 4 hours per session
5. Received dialysis treatment in a renal clinic that meets water quality standards established by the Association for the Advancement of Medical Instrumentation (AAMI)

Exclusion Criteria

1. High comorbidity measured as Charlson comorbidity Index > 8 and patients who were not expected to survive 6 months
2. Metastatic disease
3. Pregnancy
4. Younger than 18 years old

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<br> Measured using patient records at 2 year follow up:<br> 1. Hospitalization events<br> 2. Days spent in hospital<br>
Secondary Outcome Measures
NameTimeMethod
<br> Measured using patient records at 2 year follow up:<br> 1. Mortality<br> 2. Medication consumption<br>
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