Effect of ESPB on Intraoperative Remifentanil Consumption in Lumbar Spine Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Intraoperative remifentanil consumption
研究概览
简要总结
In recent years, regional anesthesia techniques have also been frequently applied to patients for pain relief. Erector spinae plane block (ESPB), is among the regional anesthesia techniques frequently used in lumbar spine surgery.
General anesthesia (GA) is the main method of anesthesia for lumbar spine surgery. However, GA can only inhibit the projection system of the cortical limbic system or hypothalamic cortex. GA cannot completely block the transmission of peripheral noxious stimulus to the central nervous system and cannot effectively inhibit the intraoperative stress response. With the addition of peripheral blocks such as ESPB, lower remifentanil consumption, and more stable hemodynamics are expected by providing preemptive analgesia in patients.
As a result of all these; it was aimed to compare the intraoperative remifentanil consumption of patients who underwent preoperative ESPB in patients who will undergo lumbar spine surgery resection under GA with those who underwent postoperative ESPB.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18 to 65 years old
- •American Society of Anesthesiologists (ASA) physical status I-II-III
- •Body mass index 18 to 30 kg/m2
- •Elective lumbar disc herniation surgery
排除标准
- •Patient refusing the procedure
- •Patients who have previously undergone spinal surgery
- •Chronic opioid or analgesic use
- •Patients who will operate under emergency conditions
- •Patients who will not undergo lumbar disc herniation surgery
研究组 & 干预措施
Preoperative Erector Spinae Plane Block
In the preoperative period, under general anesthesia, after the linear ultrasound (US) probe will be placed 2-3 cm lateral to the L3 spinous process, 15 ml of 0.25% bupivacaine will be injected into the interfacial space below the erector spinae muscle, above the transverse process. The same ESPB procedure was performed on the other side. In total, 30 ml of 0.25% bupivacaine was administered.
干预措施: Preoperative Erector Spinae Plane Block (Drug)
Postoperative Erector Spinae Plane Block
In the postoperative period, under general anesthesia, after the linear ultrasound (US) probe will be placed 2-3 cm lateral to the L3 spinous process, 15 ml of 0.25% bupivacaine will be injected into the interfacial space below the erector spinae muscle, above the transverse process. The same ESPB procedure was performed on the other side. In total, 30 ml of 0.25% bupivacaine was administered.
干预措施: Postoperative Erector Spinae Plane Block (Drug)
结局指标
主要结局
Intraoperative remifentanil consumption
时间窗: During the intraoperative period
The amount of remifentanil that patients need to maintain anesthesia during the intraoperative period will be recorded.
次要结局
- Mean arterial pressure(Perioperative period)
- Heart rate(Perioperative period)
- Pain scores(First 24 hours after surgery)
研究者
Musa Zengin
Principal İnvestigator
Ankara Etlik City Hospital