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Intravenous Hypertonic saline solution in management of patients with Diuretic Resistant Generalized Edema

Phase 3
Conditions
GENERALIZED EDEMA RESISTANT TO THERAPY.
Registration Number
IRCT20200812048380N1
Lead Sponsor
Shahid Beheshti University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
28
Inclusion Criteria

The target population for this trial was patients older than 18 years old with diffuse peripheral edema who did not respond adequately to 80 mg oral furosemide.

Exclusion Criteria

subjects candidate for hemodialysis
systolic blood pressure =80 mmHg
GFR =15ml/min
serum albumin =2.5g/dL
serum potassium =5.5mEq/L
serum sodium greater than 145mEq/L
anuric patients (urine volume =100 ml per 24 hours

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Weight loss. Timepoint: daily. Method of measurement: scale.;Serum cr. Timepoint: before and after treatment. Method of measurement: blood sample.;C systatin. Timepoint: before and after treatment. Method of measurement: blood sample.
Secondary Outcome Measures
NameTimeMethod
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