Influence of nociception-level controlled epidural anesthesia on perioperative analgesic requirements

Not Applicable

Not yet recruiting

Conditions: o specific disease
Optimisation and management of perioperative analgesia therapy

Registration Number: DRKS00034633

Lead Sponsor: Klinik für Anästhesiologie der Universitätsmedizin Mainz

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 80

Inclusion Criteria

? Written declaration of consent
? Elective surgical or diagnostic procedure under combined general and epidural anesthesia in abdominal and visceral surgery and urology

Exclusion Criteria

- Pre-existing arrhythmias such as atrial fibrillation, grade II and III AV block
- Pacemaker therapy
- Drug abuse (narcotics) or opiate habit
- Pregnancy and breastfeeding
- Chronic pain syndrome and pain therapy
- Severe PAD (grade IV)
- Simultaneous participation in another study that influences the outcome parameters

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
? Effect of NOL on perioperative analgesic requirements<br>? Effect of NOL on perioperative catecholamine requirements

Secondary Outcome Measures

Name	Time	Method
? Recording of the most important patient data such as age, height, gender, ASA classification, previous illnesses, previous medication<br>? Recording of various factors influencing NOL (perioperative stimuli such as intubation, positioning, skin incision, etc.)<br>? Recording of hemodynamic events<br>? Recording of the intraoperative volume status<br>? Recording cerebral oxygenation and autoregulation<br>? Postoperative recording of patient satisfaction and pain<br>? Preoperative recording of a cognitive deficit<br>? Postoperative recording of delirium<br>? Postoperative recording of awareness<br>? Evaluation of morbidity<br>? Length of stay in intensive care unit and length of hospital stay<br>? Mortality