NCT00397267Unknown4 期
Treatment of Acute Asthma in ER With Combination of Systemic Steroids and Inhaled Steroids
适应症
相关药物
试验速览
- 阶段
- 4 期
- 入组人数
- 120
- 试验地点
- 2
- 主要终点
- PFT improvment
研究概览
简要总结
We assume that the combination of systemic steroids and inhaled steroid in the first hour of treatment in the ER will decrease the admission rate and improve faster the pulmonary function.
120 patients refferd to the ER due to asthma attack aged 18-60 with PFR < 60% 0o predicted will participate in the study after giving informed consent.
The usual treatment in the ER is inhalation of Beta 2 short acting and I.V solumedrol 120 mg . The study group will recieve in addition 3 inhalation of Budesonide 1000 microgram each during the first hour.
The controlled group will recieve Nacl 0.9% PFR will be followed 0 30 60 120 min.
详细描述
Primary end points- PFT improvment and admission rate.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Asthmatic patients aged 18-60 with PFR < 60% of predicted
排除标准
- •Patients with other chronic diseases
- •cardiac renal hepatic etc will be excluded
结局指标
主要结局
PFT improvment
Admission rate
次要结局
未报告次要终点
研究者
研究点 (2)
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