A parallel, double-blind, randomised controlled trial to evaluate the effect of daily consumption of symbiotic yoghurt on lipid profile in mildly to moderately hypercholesterolemic men and women.

Victoria University0 个研究点目标入组 96 人开始时间: 2014年1月28日最近更新: 2020年1月13日

适应症

试验速览

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•Mild to moderate hypercholesterolemic men and women (total cholesterol level less than 6.2 mmol/L and triglyceride level less than 2.3 mmol/L), with either overweight or obesity defined by waist circumference >80 cm or Body Mass Index 25-35 kg/m2. Participants will be free of serious medical conditions such as diabetes, heart disease and malignancies, and will be non allergic to dairy or lactose, non-smoking, non-pregnant and non-lactating.

•Participants with an allergy to lactose.
•Pregnancy or lactation.
•Liver, kidney or heart disease.
•Type 1 diabetes and type 2 diabetes with insulin medication.
•The use of any medication for weight loss.
•Unable to participate for 8-week period, including preliminary information visit.
•Excessive exercisers, participating in regular physical activity in excess of moderate intensity and duration as defined by NHMRC (2005) Nutrient Reference Values, where Physical Activity Levels (PAL) are greater than or equal to 2.0. That is, participants with a lifestyle primarily involving highly active leisure, significant amounts of sport or strenuous leisure activity (30-60 mins, 4-5 times/week), or heavy occupational work (e.g. high performance athletes, farmers, construction workers, miners, forest workers).
•Participants with obesity caused by genetic factors or medication.
•Neurological, endocrinological or other major systemic disease, including malignancy.
•Acute illness or current evidence of acute or chronic inflammatory or infective disease; treatment for anemia within the past 3 months; cirrhosis or chronic hepatitis.

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