Study of the Prevalence of Polymyositis and Dermatomyositis in Normandy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 187
- 试验地点
- 1
- 主要终点
- Confirmed diagnosis of polymyositis / dermatomyositis
研究概览
简要总结
Polymyositis and dermatomyositis are characterized by the association to a myopathic syndrome, inflammatory infiltrates in the skeletal muscle. They remain, even today, an important factor of morbidity and mortality in these patients. At present, studies that evaluated the prevalence of polymyositis / dermatomyositis are very few; they were mainly recorded in the United States and Japan, the prevalence of polymyositis / dermatomyositis has been estimated between 3.5 and 21.5 cases / 100 000 (according to the old diagnostic criteria of Bohan and Peter). However, previous works are old and retrospective; above all, they have almost always been performed (90% of cases) from cases reported to the hospital, leading to selection bias and an underestimate of the true prevalence of polymyositis / dermatomyositis in the general population.
Thus, these data lead to achieve this epidemiological study, descriptive, multicenter, based on the population of Normandy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with polymyositis / dermatomyositis, meeting the diagnostic criteria for ENMC;
- •patient living Normandy ;
- •patient has been informed and has given its verbal agreement ;
排除标准
- •patients with myositis diagnosed before inclusion (including pathophysiology, clinical phenotype and therapeutic care are different from polymyositis / dermatomyositis)
结局指标
主要结局
Confirmed diagnosis of polymyositis / dermatomyositis
时间窗: approximately 1 month
recruitment of patients with polymyositis / dermatomyositis
次要结局
未报告次要终点
