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Clinical Trials/NCT04507048
NCT04507048
Completed
N/A

A Multicentric Randomized Controlled Trial Comparing the Efficacy of Passive Versus Active Educational Interventions in Increasing the Ability of Laypersons in Recognizing Skin Lesions at Risk for MELAnoma

Azienda Unità Sanitaria Locale Reggio Emilia7 sites in 1 country560 target enrollmentSeptember 1, 2019

Overview

Phase
N/A
Intervention
Not specified
Conditions
Educational Problems
Sponsor
Azienda Unità Sanitaria Locale Reggio Emilia
Enrollment
560
Locations
7
Primary Endpoint
Rate of lesions correctly evaluated as at risk
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

This study evaluates the efficacy of a passive versus an active educational intervention in increasing the ability of laypersons at low risk for melanoma development, in recognizing atypical skin melanocytic lesions. Patients will be randomized (1:1) to receive the active or the passive intervention.

Detailed Description

Almost 60-70% of primary melanomas are first detected by patients or their relatives and not by physicians. Then, it appears imperative to promote public campaigns in order to increase the awareness of laypersons on the most important rules for early identification of atypical skin lesions. The two main clinical rules are: 1. ABCD rule. According to this rule, lesions characterized by one of more of the following features: Asymmetry, irregular Borders, Color variegation and Diameter larger than 6 mm, should be considered at risk for malignancy. In order to evaluate Evolution, monitoring strategies have been implemented; 2. "ugly duckling" sign. According to this rule, a suspicious lesion tends to be different from the general nevus pattern of a given patient. The passive intervention will consist in the administration of a booklet containing the explanation of this two previous clinical rules for early detection of atypical melanocytic lesions. In the active intervention a standardized explanation will be given to the patient by a dermatologist, together with the administration of the booklet. Efficacy will be evaluated through the completion of a specific test before, immediately after and after one month the administration of the educational intervention.

Registry
clinicaltrials.gov
Start Date
September 1, 2019
End Date
September 30, 2020
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Azienda Unità Sanitaria Locale Reggio Emilia
Responsible Party
Principal Investigator
Principal Investigator

Prof.ssa Caterina Longo

Professor

Azienda Unità Sanitaria Locale Reggio Emilia

Eligibility Criteria

Inclusion Criteria

  • no personal or family history for melanoma;
  • first visit for skin examination

Exclusion Criteria

  • patients referring to know and to be already confident in the use of at least one of the tested rules.

Outcomes

Primary Outcomes

Rate of lesions correctly evaluated as at risk

Time Frame: 30 ± 2 days

Change at t1 and t2 from baseline (t0) in lesions at risk correctly identified, comparing passive and active educational intervention arms.

Secondary Outcomes

  • Rate of lesions correctly assigned to the proper risk category(30 ± 2 days)

Study Sites (7)

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