Evaluating Shear Wave Elastography as a Predictor of Extracorporeal Shock Wave Lithotripsy Outcomes and Stone Composition in Children "A Prospective Study"
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 110
- 试验地点
- 1
- 主要终点
- ESWL Success Rate
研究概览
简要总结
This prospective study aims to evaluate the role of shear wave elastography (SWE) as a non-invasive and radiation-free tool for predicting the success of extracorporeal shock wave lithotripsy (ESWL) in pediatric patients with renal stones. Currently, computed tomography (CT)-derived Hounsfield units (HU) are used to estimate stone hardness; however, repeated radiation exposure is a concern in children. SWE may provide an alternative method by assessing stone stiffness using ultrasound.
Pediatric patients under 18 years with renal stones (6-20 mm) scheduled for ESWL will be included. SWE measurements will be performed prior to treatment, and patients will be followed for 3 months to assess treatment outcomes. The primary outcome is ESWL success, while secondary outcomes include correlation between SWE and HU, number of ESWL sessions required, prediction of stone composition, and assessment of the relationship between SWE measurements and stone composition.
This study seeks to determine whether SWE can serve as a reliable predictor of ESWL outcomes, correlate with stone composition, and reduce the need for radiation-based imaging in children.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Year 至 18 Years(Child, Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Inclusion criteria:
- •Single Renal stones measured 6- 20 mm in maximal dimension.
- •ESWL will be planned as the first line of treatment.
排除标准
- •Patients with internal ureteral stent.
- •ureteral stones.
- •abnormal renal anatomies (pelvic kidney, horseshoe kidney, and rotational anomaly).
- •active UTI at time of ESWL.
- •coagulopathy .
- •Exclusion Criteria:
研究组 & 干预措施
Pediatric Patients Undergoing ESWL
Pediatric patients (<18 years) with renal stones (6-20 mm) undergoing extracorporeal shock wave lithotripsy (ESWL). All patients will undergo baseline shear wave elastography (SWE) assessment prior to treatment. Patients will be followed for 3 months to evaluate ESWL success and its correlation with SWE measurements, Hounsfield units (HU), and stone composition.
结局指标
主要结局
ESWL Success Rate
时间窗: 3 months with maximum 3 sessions ESWL
Treatment success defined as absence of stone fragments or presence of clinically insignificant residual fragments ≤2 mm on imaging, without symptoms, obstruction, or urinary tract infection.
次要结局
- Secondary Outcomes Related to SWE and ESWL(Up to 3 months after ESWL)
研究者
Mahmoud Abdallah
lecturer of urology faculty of medicine Beni Suef university
Beni-Suef University
