ISRCTN87042095
Active, not recruiting
未知
Hypobaric oxygen during cardiopulmonary bypass to reduce gaseous micro-emboli during cardiac surgery: a randomized controlled trial
niversity Hospitals Bristol and Western NHS Foundation Trust0 sites40 target enrollmentJune 13, 2022
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- niversity Hospitals Bristol and Western NHS Foundation Trust
- Enrollment
- 40
- Status
- Active, not recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Age \> \= 40 years
- •2\. Having elective or urgent CABG or AVR (with or without an associated CABG procedure AVR±CABG) via a partial or full sternotomy using using central aortic perfusion cannulae CPB.
Exclusion Criteria
- •1\. History of clinical stroke within 3 months prior to randomization
- •2\. Cardiac catheterisation within 3 days of the planned surgery
- •3\. Cerebral and/or aortic arch arteriography or interventions within 3 days of the planned surgery
- •4\. Active endocarditis at time of randomisation
- •5\. Planned concomitant aortic procedure such as root replacement
- •6\. Clinical signs of cardiogenic shock or treatment with IV inotropic therapy prior to randomization
- •7\. Myocardial infarction in the previous 4 days
- •8\. Participation in an interventional (drug or device) trial
- •9\. Unable to provide written informed consent
- •10\. Prisoner
Outcomes
Primary Outcomes
Not specified
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