Iodine Status at Several Time Points During 48 Hours After Intake of Sushi and Seaweed Salad- a Randomized Crossover Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 22
- 试验地点
- 1
- 主要终点
- Urinary iodine concentration during 48 hours
研究概览
简要总结
Seaweed is becoming increasingly popular in the Western part of the world, especially sushi wrapped in nori and seaweed salad, also called wakame. There are limited data on the iodine content of different seaweed products in the Norwegian Food composition table. Furthermore, there is limited available research regarding in vivo bioavailability of iodine from seaweeds. The objective of this study is to assess whether iodine from a sushi meal (with nori, Porphyra spp), and a wakame salad (Undaria pinnatifida) has similar bioavailability as a potassium iodide reference supplement of similar iodine content.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •healthy women aged 18 to 40 years
排除标准
- •pregnant or lactating
- •known thyroid disease or thyroid autoimmunity,
- •planning to conceive,
- •known kidney problems or kidney disease.
- •women with coeliac disease could not participate due to possible gluten exposure from the wakame salad
研究组 & 干预措施
Potassium iodide supplement
225 microgram of iodine per tablet
干预措施: Sushi and wakame salad (Other)
Sushi and wakame salad
231 microgram of iodine per serving
干预措施: Sushi and wakame salad (Other)
结局指标
主要结局
Urinary iodine concentration during 48 hours
时间窗: 48 hours
Urinary iodine concentration after ingestion of the intervention/supplement during 48 hours by fixed time-intervals
Bio-availability of iodine in the intervention/supplement
时间窗: 48 hours
Calculation of the bio-availability of iodine in the intervention/supplement
次要结局
未报告次要终点