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Clinical Trials/NCT06093412
NCT06093412
Completed
Not Applicable

Application of Unilateral Epidural Anesthesia in Older Patients With Hip Fracture

Sichuan Provincial People's Hospital1 site in 1 country106 target enrollmentJanuary 1, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Spinal Anesthesia
Sponsor
Sichuan Provincial People's Hospital
Enrollment
106
Locations
1
Primary Endpoint
Hemodynamic change
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Because of population ageing, fragility fractures have become a huge burden on healthcare systems and wider society. Fractures result in a sharp drop in both short-term and long-term quality of life, they have a strong influence on activities of daily living and mobility, and they are associated with a significant increase in 1-year mortality (18%-36%). Surgery can benefit elderly patients with hip fractures to an extent, but it entails inevitable risks, particularly with respect to general anesthesia. In recent years unilateral spinal anesthesia has attracted attention due to the advantages of hemodynamic stability, reduced anesthetic dosage, and sufficient sensory block.

On the basis of a previous study, in the current study anesthetics were directly implanted into the unilateral epidural space in elderly patients with hip fractures prior to the completion of surgery. Data from 106 patients with old hip fractures who had undergone surgical treatment incorporating unilateral epidural anesthesia (UEA) or combined lumbar and epidural anesthesia were retrospectively analyzed in an attempt to provide a feasible solution for this kind of patients' anesthesia.

Detailed Description

Surgery can benefit elderly patients with hip fractures to an extent, but it entails inevitable risks, particularly with respect to general anesthesia. In recent years unilateral spinal anesthesia has attracted attention due to the advantages of hemodynamic stability, reduced anesthetic dosage, and sufficient sensory block. On the basis of a previous study, in the current study anesthetics were directly implanted into the unilateral epidural space in elderly patients with hip fractures prior to the completion of surgery.

Registry
clinicaltrials.gov
Start Date
January 1, 2018
End Date
June 30, 2021
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Sichuan Provincial People's Hospital
Responsible Party
Principal Investigator
Principal Investigator

Peng Liu

Professor

Sichuan Provincial People's Hospital

Eligibility Criteria

Inclusion Criteria

  • had a fracture of a proximal femur were aged \> 65 years the fracture occurred within 2 weeks of receiving treatment with comorbidities including pulmonary disease, arrhythmia, senile valve disease or lacunar infarction underwent intraspinal anesthesia during surgery

Exclusion Criteria

  • had a secondary fracture after endoprosthetic reconstruction or intramedullary nail had a pathological fracture caused by tumor or tuberculosis condition was accompanied by lower limb nerve dysfunction had a cognitive or psychiatric disorder coagulation disorders hospitalization data were incomplete.

Outcomes

Primary Outcomes

Hemodynamic change

Time Frame: Within 20 minutes after anesthesia

Oxygen saturation

Secondary Outcomes

  • Dose of ephedrine use(During the surgery period)

Study Sites (1)

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