Changes in the Diameter of Retinal Vessels After Remote Ischemic Conditioning in Patients With Type 1 Diabetes

Not Applicable

Completed

• Conditions: Retinal Ischemia; Ischemia; Diabetes Complications; Diabetes Mellitus, Type 1
• Interventions: Other: Remote Ischemic Conditioning

• Registration Number: NCT03906383
• Lead Sponsor: University of Aarhus

Brief Summary

Remote ischemic conditioning (RIC) is a therapeutic strategy for protecting organs or tissue against the detrimental effects of acute ischemia-reperfusion injury. It remains unknown whether this can be used in retinal ischemic diseases. The purpose of the present study is to examine if the autoregulation of retinal vessel diameters in diabetic patients change after remote ischemic conditioning and if the observations are different from what have been observed in normal persons.

Detailed Description

Not available

Basic Information
|
Recruitment & Eligibility
|
Study & Design
|
Trial Locations

Study Timeline

• Study Start: 2017-11-21
• Primary Completion: 2018-10-16
• Study Completion: 2018-10-16
• Status Verified: 2019-04
• Study First Submitted: 2019-04-04
• Study First Submitted QC: 2019-04-04
• Study First Posted: 2019-04-08
• Last Update Submitted: 2019-04-12
• Last Update Posted: 2019-04-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 21

Inclusion Criteria

• Diabetes type 1
• Diabetic retinopathy

Read More

Exclusion Criteria

• Previous treatment for diabetic retinopathy
• Other ocular and systemic diseases requiring treatment
• Pregnancy or lactation

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Remote Ischemic Conditioning	Remote Ischemic Conditioning	-

Primary Outcome Measures

Name	Time	Method
Diameter change of retinal vessels	Immediately after and one hour after	Diameter change from baseline in percent.

Trial Locations

Locations (1)

University of Aarhus; 🇩🇰 Aarhus C, Danmark, Denmark