T Wave Alternans in Hemodialysis

Completed

• Conditions: End Stage Renal Disease; Coronary Heart Disease; Congestive Heart Failure

• Registration Number: NCT00296543
• Lead Sponsor: Indiana University School of Medicine

Brief Summary

The purpose of this study is to determine if the hemodialysis procedure changes the risk for cardiac arrest in patients.

Detailed Description

One-third to one-quarter of hemodialysis patients die of sudden cardiac death (SCD). The hemodialysis procedure may theoretically increase the risk of SCD. This study uses T wave alternans, a noninvasive marker of SCD, to objectively determine whether the hemodialysis procedure alters the risk of SCD in hemodialysis patients.

Study Timeline

• Study Start: 2005-10
• Study First Submitted: 2006-02-23
• Study First Submitted QC: 2006-02-23
• Study First Posted: 2006-02-27
• Study Completion: 2008-08
• Status Verified: 2011-06
• Last Update Submitted: 2011-06-17
• Last Update Posted: 2011-06-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• 18 years of age or older
• Normal sinus rhythm

Exclusion Criteria

• Inability to give written informed consent
• Active cardiac ischemia
• Pacemaker
• Inability to perform a brief walking treadmill test

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Indiana University School of Medicine; 🇺🇸 Indianapolis, Indiana, United States