Prospective MRI Evaluation of Cavernous Sinus Invasion by Pituitary Adenoma Using Deep Learning Based Denoising
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 67
- 试验地点
- 1
- 主要终点
- Cavernous sinus invasion
研究概览
简要总结
Preoperative evaluation of cavernous sinus invasion by pituitary adenoma is critical for performing safe operation and deciding on surgical extent as well as for treatment success. Because of the small size of the pituitary gland and sellar fossa, determining the exact relationship between the pituitary adenoma and cavernous sinus can be challenging. Performing thin slice thickness MRI may be beneficial but is inevitably associated with increased noise level. By applying deep learning based denoising algorithm, diagnosis of cavernous sinus invasion by pituitary adenoma may be improved.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing preoperative brain MR for pituitary adenoma
排除标准
- •Patients who have any type of bioimplant activated by mechanical, electronic, or magnetic means (e.g., cochlear implants, pacemakers, neurostimulators, biostimulates, electronic infusion pumps, etc), because such devices may be displaced or malfunction
- •Patients who are pregnant or breast feeding; urine pregnancy test will be performed on women of child bearing potential
- •Poor MRI image quality due to artifacts
研究组 & 干预措施
Deep learning based denoising MR
1 mm slice thickness coronal contrast-enhanced T1 weighted imaging with deep learning based denoising vs. 3 mm slice thickness coronal contrast-enhanced T1 weighted imaging
干预措施: MRI with deep learning based denoising (Diagnostic Test)
结局指标
主要结局
Cavernous sinus invasion
时间窗: Within 1 week
Presence or absence of cavernous sinus invasion determined surgically
次要结局
- Margin of pituitary adenoma (well-delineated, poorly delineated) on the MRI(Within 1 week)
- Size of pituitary adenoma (in mm), laterality of pituitary adenoma (unilateral or bilateral) on the MRI(Within 1 week)
研究者
Ho Sung Kim
Professor
Asan Medical Center