The Comparison of The Effect of Eicosapentaenoic Acid and Docosahexaenoic Acid on Helicobacter pylori Infection Eradication and Some Serum Inflammatory Factors

Not Applicable

• Conditions: Helicobacter pylori.

• Registration Number: IRCT201101122709N16
• Lead Sponsor: Vive-chancellor for Research, Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 105

Inclusion Criteria

- positive stool antigen test result
- no history of pharmaceutical treatment for infection eradication
- no gastric surgery
- no history of peptic ulcer
- no any disease that cause inflammation & increase of serum inflammatori markers level such as diabetes, CVD, respiratoryinflammations such as asthma,...
- no consumption of any drug other than prescribed drugs during the study
- no consumption of antibiotic or bismut during 2 months before the trial
- no consumption of antioxidant supplements such as Se, Zn, beta-caroten,... at least 3 months before the trial
- no consumption of omega-3 supplements at least 3 months before the trial
- no smoking
- BMI less than 30
- age between 20-60 years old
-leaning to cooperation
Exclusion criteria:
- no leaning to continuing the cooperation
- any change in type or dose of prescribed drugs
- any change in daily diet or physical activity
- consumption of any antioxidant supplement
- consumption of less than 70% of supplements given to patients at the start of the study

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Helicobacter pylori infection eradication. Timepoint: before & after intervention (after 12 weeks intervention). Method of measurement: stool antigen test.;Serum level of Il-6. Timepoint: before & after intervention (after 12 weeks intervention). Method of measurement: ELISA kitt.;Serum level of Il-8. Timepoint: before & after intervention (after 12 weeks intervention). Method of measurement: ELISA kitt.;Serum level of hs-CRP. Timepoint: before & after intervention (after 12 weeks intervention). Method of measurement: ELISA kitt.;Serum level of TAC. Timepoint: before & after intervention (after 12 weeks intervention). Method of measurement: colorimetry (FRAP).