Serum iron profile and bone marrow iron stores in iron deficiency anemia and anemia of chronic disease

•       Anemia is not a disease,but a manifestation of many underlying disease. It is a common problem in   clinical practice. •        Anemia is defined as a reduction of the totalcirculating red cell mass below normal limits.[1] •       Among various types ofanemia, Iron deficiency anemia is the most common  nutritional deficiency seen in India. Routinescreening as well as specific tests are done to diagnose anemia. •       Bone marrow examinationis becoming highly important for diagnosis and therapeutic indication ofseveral haematological and other illnesses.[2] Gold standardexamination is Bone marrow Microsopy in these conditions. •       Bone marrow aspirationand trephine biopsies are to aid cytological, immunophenotypical and molecular genetic . This study propounds theserum iron profile and bone marrow iron stores as diagnostic tool to find outwhether these biochemical assays can help to correlate the dynamics ofmetabolic reactions in the conditions and to further assess the role ofmorphological grading of iron stores in bone marrow aspiration and trephinebiopsies in cases of anemia.