Effect of Aspirin and Atorvastatin on liver function in patients with hepatic failure
Phase 2
- Conditions
- iver Cirhhosis.Chronic hepatic failure
- Registration Number
- IRCT2016120531252N1
- Lead Sponsor
- Office of Research & Technology, Qom University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
patients with compensated cryptogenic cirrhosis; living in Qom; Age of 18 to 75 years; patient without another type of cirrhosis; who have not been treated with statins; patients with serum LDL>70; Patients with PLT>50000
Exclusion criteria: Increased liver enzymes more than three times, three months after treatment; Lack of cooperation in the proper use of drugs; Statin-induced myopathy; use of Fibrates, Erythromycin, and other drugs that suppressed metabolism of p450 liver enzyme
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sevirity of fibrosis. Timepoint: six months after begining intervention. Method of measurement: kpa with fibroscan.;Liver function. Timepoint: six months after begining intervention. Method of measurement: child score.
- Secondary Outcome Measures
Name Time Method iver enzymes levels. Timepoint: six month after begining of intervention. Method of measurement: IU/L.