The effect of Magnesium sulphate on increased intra ocular pressure due to general anesthesia
Phase 3
- Conditions
- Z40 - Z41Persons encountering health services for specific procedures and health care.Persons encountering health services for specific procedures and health care
- Registration Number
- IRCT138812013376N1
- Lead Sponsor
- Vice Chancellor for Research of Shiraz University of Medical Science,Anesthesia department
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 180
Inclusion Criteria
180 patients (ASA I) healthy adult, (18 to 38years old, both man and woman) that were scheduled for elective non ocular surgery (ENT and ambulatory surgery that needed tracheal intubation), were selected. exclusion criteria: The patients with specific major hepatic, renal and cardio-vascular disease as well as those known to have allergic reaction to magnesium sulphate or other drugs on basis of the history of patients, and hypermagnesemia, hypocalcemia on the basis on lab data, anuria, heart block (ECG), pregnancy, any degree of renal insufficiency, digitalised patients, positive history of glaucoma, or intra ocular hypertension, and patients who refused to participate in this study, were excluded.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Iop (Intra ocular pressure). Timepoint: In 4 stage (T1:Before induction of anesthesia ,T2 :Just before intubation , T3:1 minute after intubation ,T4:5 minute after intubation. Method of measurement: TONOPEN Instrument.
- Secondary Outcome Measures
Name Time Method Systolic BP. Timepoint: 4 stages ; T1 :Before Induction of anesthesia , T2 : just before intubation ,T3 : 1 minute after intubation, T4 :5 minute after intubation. Method of measurement: NIBP monitoring.;Diastolic BP. Timepoint: 4 stages ; T1 :Before Induction of anesthesia , T2 : just before intubation ,T3 : 1 minute after intubation, T4 :5 minute after intubation. Method of measurement: NIBP monitoring.;Mean Arterial Pressure. Timepoint: 4 stages ; T1 :Before Induction of anesthesia , T2 : just before intubation ,T3 : 1 minute after intubation, T4 :5 minute after intubation. Method of measurement: NIBP monitoring.;Heart Rate. Timepoint: 4 stages ; T1 :Before Induction of anesthesia , T2 : just before intubation ,T3 : 1 minute after intubation, T4 :5 minute after intubation. Method of measurement: EKG monitoring.