Effects of brain training in Huntington’s disease

Not Applicable

Active, not recruiting

• Conditions: Huntington's disease; Cognitive impairment; Dementia; Neurological - Neurodegenerative diseases

• Registration Number: ACTRN12622000908730
• Lead Sponsor: Monash University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-06-27
• Last Update Posted: 5 February 2024

Recruitment & Eligibility

• Status: Active, not recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Inclusion criteria include:
(a) Genetically positive for Huntington’s disease (HD)
(b) Premanifest disease or early-stage manifest disease (total functional capacity [TFC] = 7-13)
(c) 18+ years of age
(d) Access to computer with Internet connection

Exclusion Criteria

Exclusion criteria include:
(a) Absence of known genetic confirmation for HD
(b) Late-stage disease (TFC < 7)
(c) Under 18 years of age
(d) Diagnosis of any major neurological or psychiatric condition other than HD (besides anxiety or depression), history of substance abuse or head injury
(e) Severe depression and anxiety symptoms (score > 14 on either HADS subscale)
(f) Unstable dose of medication for depression and anxiety in the last 6 months

Additional exclusion criteria if undergoing MRI:
(a) Left-handed
(b) Currently pregnant
(c) Other MRI contraindications

Study & Design

• Study Type: Interventional
• Study Design: Not specified