A clinical trial to study the effectiveness of autologous platelet rich fibrin therapy in chronic non-healing cutaneous ulcers
- Conditions
- Health Condition 1: L088- Other specified local infections of the skin and subcutaneous tissue
- Registration Number
- CTRI/2023/06/053870
- Lead Sponsor
- IPGME&R and SSKM Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1)All patients with chronic non-healing cutaneous ulcer more than 6 weeks duration attending
dermatology OPD of IPGME&R, SSKM HOSPITAL above 18 years of age and willing to
participate.
2)Ulcer area 0.5 sq cm â?? 50 sq cm
3) Hemoglobin more than 9 g/dl
4)Platelet count more than 1,00,000 per cubic mm
5)Fasting blood sugar more than 140 mg/dl
1)Ulcer area more than 50 sq cm
2)Ulcer exposed with bone, muscle, ligament or tendon
3)Pregnant and lactating woman
4)Ulcers with active discharge or infection
5)Patients with uncontrolled systemic disease
6)Patients on anti-coagulant and immunosuppressive therapy
7)Patients with inherited or acquired immunodeficiency
8)Patients with history of allergy to hydrocolloid gel dressing, colloidal silver and clot
accelerator
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Area of the ulcer will be measured at baseline and the decrease in area compared to the baseline value.Timepoint: Every week for 6 weeks
- Secondary Outcome Measures
Name Time Method Amount of exudate and bacterial contaminationTimepoint: Every week for 6 weeks