to study effects of radial artery cannulation with intrarterial catheter on perfusion.

Active, not recruiting

• Conditions: Intraoperative hemorrhage and hematoma of a nervous system organ or structure complicating a procedure, (2) ICD-10 Condition: G973||Intraoperative hemorrhage and hematoma of a nervous system organ or structure complicating a procedure, (3) ICD-10 Condition: G973||Intraoperative hemorrhage and hematoma of a nervous system organ or structure complicating a procedure,

• Registration Number: CTRI/2021/07/035209
• Lead Sponsor: Shri Guru Ram Rai Institute of Medical Health Sciences

Brief Summary

After getting approval frominstitutional ethical committee, written informed consent will be obtained fromall those patients and/or attendants  whowill fulfill the inclusion criteria. Exclusion criteria are age <18 or>90, Peripheral vascular diseases  upper limb surgeries planned radial arteryharvesting recent trans radial intervention, recent acute myocardial infarctionor percutaneous coronary intervention (PCI), active malignancy, autoimmunedisease, bleeding disorders, recent stroke, functional impairment of the non-dominantarm, pregnancy, severe anemia or thrombocytopenia. Radial artery cannulation will be done in the non-dominant hand of thesubject using catheter-over-needle technique - 20-gauge, 1.75-in. (4.45-cm)polyurethane catheter over 22-gauge introducer needle or catheter-over-wiretechnique (modified Seldinger) - 20-gauge peripheral artery catheter kit withintegrated wire and catheter. Perfusion index will be measured using hand heldpulse oximeter placed on the index finger 1 minute before the intervention(baseline) and  at 1, 10 and 30 minutesafter the intervention. The PI ratio will be calculatedas the ratio between the PI at 10 minutes after intervention and the baselinePI. Comparison between the values of PI before and after the intervention will be done and statisticallyassessed. A comparison between the cannulated and non cannulated limb will alsobe performed in every patient.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-02-08
• Last Update Posted: 2022-10-04

Recruitment & Eligibility

• Status: Closed to Recruitment of Participants
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

patients undergoing surgery and requiring blood pressure monitoring.

Exclusion Criteria

Peripheral vascular diseases upper limb surgeries planned radial artery harvesting recent trans radial intervention, recent acute myocardial infarction or percutaneous coronary intervention (PCI), active malignancy, autoimmune disease, bleeding disorders, recent stroke, functional impairment of the non-dominant arm, pregnancy, severe anemia or thrombocytopenia.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary objective is to determine the impact of radial artery cannulation on delta change in digital perfusion index	pre insertion, 1, 10, 30 mins after insertion

Secondary Outcome Measures

Name	Time	Method
Secondary objectives is to study change in perfusion index with time (pre insertion, 1, 10, 30 mins after insertion) after radial artery cannulation and to compare perfusion index in cannulated and non-cannulated hand as well as in different digits	pre insertion, 1, 10, 30 mins after insertion

Trial Locations

Locations (1)

Shri Guru Ram Rai Institute of Medical & Health Sciences; 🇮🇳 Dehradun, UTTARANCHAL, India

Shri Guru Ram Rai Institute of Medical & Health Sciences

🇮🇳Dehradun, UTTARANCHAL, India

Nishith Govil

Principal investigator

8126101759

nishithgovil@rediffmail.com