Predictive Factors of Pelvic Magnetic Resonance in the Response of Arterial Embolization of Uterine Leiomyoma
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Leiomyoma reduction in patients who underwent uterine artery embolization
研究概览
简要总结
The purpose of this study is to determine predictive factors in the pelvic magnetic resonance in the response of arterial embolization of uterine leiomyoma.
详细描述
This study followed symptomatic premenopausal women with uterine leiomyoma who underwent uterine artery embolization (UAE). Treatment was accompanied by magnetic resonance imaging of both the volume of the entire uterus and the leiomyomas one month before and six months after UAE. This patients were treated at the Uterine Leiomyoma Sector of the Department of Obstetrics and Gynecology, Medicine College of the University of São Paulo. In this study, the investigators examined 179 leiomyomas in 50 patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •ultrasound diagnosis of uterine leiomyoma
- •presence of symptoms (menorrhalgia and/or pelvic pain)
- •indication for UAE(the desire to keep the uterus and/or contraindications for surgery).
排除标准
- •malignant genital neoplasms
- •pelvic inflammatory disease
- •allergy to iodinated contrast
- •coagulopathy, renal failure
- •vasculitis
- •pelvic irradiation
- •pregnancy
- •subserosal leiomyoma with a pedicle smaller than 50% of diameter of the fibroid.
结局指标
主要结局
Leiomyoma reduction in patients who underwent uterine artery embolization
时间窗: One month before(baseline) and six month after the embolization
Use the magnetic resonanse to evaluate factors that predicted leiomyoma reduction in patients who underwent uterine artery embolization
次要结局
未报告次要终点
研究者
Eduardo Zlotnik
Principal Investigator
Hospital Israelita Albert Einstein