A Randomized Study to Test Peripheral Venous Catheter Lock Therapy With Either Heparin or Saline in Patients Admitted to the Internal Medicine Department
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 354
- 试验地点
- 2
- 主要终点
- complications
研究概览
简要总结
A clinical, prospective. controlled and randomized study with patients with a peripheral venous catheter. Patients will be randomized to either receive heparin or saline. The investigators will monitored the clinical out come to further evaluate catheter colonization rate, phlebitis rate, days of hospital stay, antimicrobial costs, and adverse effects.
详细描述
The need of use of peripheral venous catheters and the importance of a proper management to avoid catheter colonization or phlebitis requires two possible preventive approaches: lock therapy with heparin or saline.
Heparin demonstrated its efficacy in central venous catheters, but there are still controversies of whether it is useful in peripheral venous catheters.
Objectives To compare the efficacy of heparin in peripheral venous catheters lock versus saline for the prevention of colonization and phlebitis in patients admitted to an Internal Medicine Department.
Methods: A clinical, prospective. controlled and randomized study with patients with a peripheral venous catheter.
Patients will be randomized to either receive heparin or saline. The investigators will monitored the clinical out come to further evaluate catheter colonization rate, phlebitis rate, days of hospital stay, antimicrobial costs, and adverse effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with inserted PV Catheter within 24h from admission in internal medicine
排除标准
- •hypersensibility to heparin
- •active hemorrhage
- •coagulation alterations
结局指标
主要结局
complications
时间窗: Daily from catheter insertion until catheter withdraw(estimated 10 days)
prevention of colonization(superficial and tip culture) and phlebitis(visual inflammation of entrance of catheter insertion) .
次要结局
- catheter related infection rate(Through study completion( estimated 2 year after Last patient in))
- adverse events(number of catheter obstructions and coagulation alterations)(Through study completion (2 year afterLast patient in))