A Randomized Study to Test Peripheral Venous Catheter Lock Therapy With Either Heparin or Saline in Patients Admitted to the Internal Medicine Department
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Catheter-Related Infections
- Sponsor
- Hospital General Universitario Gregorio Marañon
- Enrollment
- 354
- Locations
- 1
- Primary Endpoint
- complications
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
A clinical, prospective. controlled and randomized study with patients with a peripheral venous catheter. Patients will be randomized to either receive heparin or saline. The investigators will monitored the clinical out come to further evaluate catheter colonization rate, phlebitis rate, days of hospital stay, antimicrobial costs, and adverse effects.
Detailed Description
The need of use of peripheral venous catheters and the importance of a proper management to avoid catheter colonization or phlebitis requires two possible preventive approaches: lock therapy with heparin or saline. Heparin demonstrated its efficacy in central venous catheters, but there are still controversies of whether it is useful in peripheral venous catheters. Objectives To compare the efficacy of heparin in peripheral venous catheters lock versus saline for the prevention of colonization and phlebitis in patients admitted to an Internal Medicine Department. Methods: A clinical, prospective. controlled and randomized study with patients with a peripheral venous catheter. Patients will be randomized to either receive heparin or saline. The investigators will monitored the clinical out come to further evaluate catheter colonization rate, phlebitis rate, days of hospital stay, antimicrobial costs, and adverse effects.
Investigators
Eligibility Criteria
Inclusion Criteria
- •patients with inserted PV Catheter within 24h from admission in internal medicine
Exclusion Criteria
- •hypersensibility to heparin
- •active hemorrhage
- •coagulation alterations
Outcomes
Primary Outcomes
complications
Time Frame: Daily from catheter insertion until catheter withdraw(estimated 10 days)
prevention of colonization(superficial and tip culture) and phlebitis(visual inflammation of entrance of catheter insertion) .
Secondary Outcomes
- catheter related infection rate(Through study completion( estimated 2 year after Last patient in))
- adverse events(number of catheter obstructions and coagulation alterations)(Through study completion (2 year afterLast patient in))