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临床试验/NL-OMON44893
NL-OMON44893已完成不适用

Cerebral perfusion in patients with severe aortic valve stenosis undergoing aortic valve replacement. - Cerebral perfusion in patients with severe aortic valve stenosis

Academisch Medisch Centrum0 个研究点目标入组 95 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
95

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 至 99(—)

入选标准

  • Cohort A (N<=30):
  • * Age between 50-75 years
  • * Presence of aortic stenosis (aortic valve area less than 1 cm2)
  • * Eligible for a surgical aortic valve replacement (AVR)
  • * Expected aortic valve size of 23-25 mm;Cohort B (N<=30):
  • Age between 50-95 years
  • * Presence of aortic stenosis (aortic valve area less than 1 cm2)
  • * Eligible for transcatheter aorta valve implantation (TAVI)

排除标准

  • * Additional complex surgical procedures indicated (e.g. restoration of aortic root)
  • * Medical history of neurological disease, active malignant disease/ cardio- toxic treatment and/or venous insufficiency
  • * Contraindication to MRI exposure (*vragenlijst MRI onderzoek*)
  • * Smoking or having smoked less than 10 years ago;Cohort B:
  • * Medical history neurological disease, active malignant disease/ cardio- toxic treatment and/or venous insufficiency
  • * Contraindication to MRI exposure (*vragenlijst MRI onderzoek*)

研究者

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