ACTRN12615000718549
Completed
未知
In patients with interstitial lung disease requiring histopathologic evaluation for diagnosis, are the transbronchial lung cryobiopsy (TBLC) and the gold-standard video-assisted thoracoscopic surgical (VATS) lung biopsy, similar in their diagnostic yield?
auren Troy0 sites65 target enrollmentJuly 10, 2015
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Interstitial Lung Disease
- Sponsor
- auren Troy
- Enrollment
- 65
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients assessed as requiring histopathology for the diagnosis of their ILD (at specialist multidisciplinary team meetings), and considered suitable for VATS lung biopsy.
Exclusion Criteria
- •\* Age \> 80
- •\* Resting oxyhaemoglobin saturation under 90%
- •\* Platelets less than 100
- •\* INR \> 1\.5
- •\* Advanced comorbidities (including poorly controlled systemic hypertension, congestive cardiac failure, unstable angina, significant stroke).
- •\* History of of adverse reaction to general anaesthesia
- •\* Inability to provide informed consent
- •\* Systolic pulmonary artery pressure over 40mmHg on echocardiogram or evidence of right ventricular dysfunction
- •\* Inability to withhold anti\-platelet therapy (eg aspirin or clopidogrel)
Outcomes
Primary Outcomes
Not specified
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