Serum Squamous Cell Carcinoma Antigen Level and Tumor Volume in Head and Neck Cancer

Completed

• Conditions: Head and Neck Cancer
• Interventions: Other: Non-interventional study

• Registration Number: NCT02879968
• Lead Sponsor: Prince of Songkla University

Brief Summary

Correlation between serum squamous cell carcinoma antigen level and tumor volume in Head and Neck Cancer is to determine a correlation between level of serum squamous cell carcinoma antigen and tumor volume in Head and Neck Caner measured by cross-sectional imaging.

Detailed Description

The study is a cross-sectional study. A single measurement of serum squamous cell carcinoma antigen level is performed in the eligible Head and Neck squamous cell carcinoma patients.

The study tool measuring serum squamous cell carcinoma antigen level is ARCHITECT SCC (Abbott).

The gross tumor volume in the cross sectional imaging obtained within 2 weeks of each patient is calculated with the typical ellipsoid formula.

Correlation between both parameters will be determined.

Study Timeline

• Study Start: 2016-08
• Study First Submitted: 2016-08-23
• Study First Submitted QC: 2016-08-25
• Study First Posted: 2016-08-26
• Primary Completion: 2018-08
• Study Completion: 2018-08
• Status Verified: 2020-03
• Last Update Submitted: 2020-03-02
• Last Update Posted: 2020-03-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

• Histologically proven squamous cell carcinoma in Head and Neck
• Getting a cross-sectional imaging of Head and Neck within 2 weeks of collecting serum squamous cell carcinoma antigen

Exclusion Criteria

• Metastatic disease
• Accompanied Non-Head and Neck squamous cell carcinoma
• Nasopharyngeal, thyroid, salivary, nose and paranasal sinus carcinoma
• Skin disease: eczema, erythrodermic epidermitis, pemphigus, and psoriasis
• Pulmonary disease: tuberculosis, adult respiratory distress syndrome, pulmonary infiltration with eosinophilia, sarcoidosis, and bronchogenic cyst
• Renal failure
• Using antihistamine eye drops

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Head and Neck squamous cell carcinoma	Non-interventional study	A single measurement of serum squamous cell carcinoma antigen level is performed in the eligible Head and Neck squamous cell carcinoma patients. The study tool measuring serum squamous cell carcinoma antigen level is ARCHITECT SCC (Abbott). The gross tumor volume in the cross sectional imaging obtained within 2 weeks of each patient is calculated with the typical ellipsoid formula.

Primary Outcome Measures

Name	Time	Method
Correlation between serum squamous cell carcinoma antigen and tumor volume	2 weeks

Trial Locations

Locations (1)

Faculty of Medicine, Prince of Songkla University; 🇹🇭 Hadyai, Songkhla, Thailand